One Piece Odyssey Natural Underground Enemies is a find-and-kill type of quest, where you will have to locate the Berserk Wicked Mice and take them out.
It seems easy, but the most challenging part is finding the Berserk Wicked Mice while trying not to get lost in the sewers.
So, to avoid that, we will explain where to find the Berserk Wicked Mice and how to complete Natural Underground Enemies side story in One Piece Odyssey.
How To Start Natural Underground Enemies Side Story In One Piece Odyssey
Natural Underground Enemies side story becomes available after you fully complete Chapter 4 and return to the mysterious island.
After you progress through Chapter 5, you’ll have a chance to return to Water Seven and complete more side stories or bounties to get rewards and use them in your future adventures.
To start the Natural Underground Enemies quest, fast-travel to the Water Seven City Area Eastern Area or Mayoral Residence Plaza and move to the eastern part of the map in the Canal Restaurant.
We’ve also marked the exact location of the NPC on the map below.

Immediately after crossing the bridge east, you’ll see a Franky Familly Follower crying with no shirt and yellow hair.
Talk to Franky Familly Follower to begin the Natural Underground Enemies quest.
Where To Find Berserk Wicked Mice In One Piece Odyssey
The objective of the side story is to find and kill the Berserk Wicked Mice, which are hiding in the sewers.
To quickly enter the sewers, speak with the tall and skinny Franky Familly Follower near the quest giver, who will open up the sewer hole and take you to the elevator inside the sewers.
Interact with the elevator and head down to basement level two. From the elevator, you’ll have to reach the eastern part of the sewers.

In the image above, you’ll see the exact location of the Berserk Wicked Mice in One Piece Odyssey.
After you make your way through the sewers with Luffy, you’ll find a pack of rats laughing next to each other.

Get close to them to begin the battle. After you successfully the Berserk Wicked Mice, return to the Franky Familly Follower location to complete the Natural Underground Enemies side story.
As a token of gratitude for the help you’ve provided, you’ll receive the following rewards:
- Mouse Repellent
- 36,000 Berries
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